| Identification | Back Directory | [Name]
9-KETO FLUPROSTENOL | [CAS]
156406-33-6 | [Synonyms]
9-KETO FLUPROSTENOL
Travoprost Impurity 34
FLUPROSTENOL PROSTAGLANDIN E2
Travoprost Impurity 15（9-keto Fluprostenol）
9-OXO-11ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR PROSTA-5Z,13E-DIEN-1-OIC ACID
5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-5-oxocyclopentyl]-, (5Z)- | [Molecular Formula]
C23H27F3O6 | [MDL Number]
MFCD05865089 | [MOL File]
156406-33-6.mol | [Molecular Weight]
456.45 |
| Hazard Information | Back Directory | [Description]
9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist. However, no studies on the pharmacology of this compound have been published to date. | [Uses]
9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist. However, no studies on the pharmacology of this compound have been published to date. | [Uses]
9-Keto Fluprostenol is an impurity of Fluprostenol (F500753), a FP prostaglandin receptor. |
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