Identification | Back Directory | [Name]
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN | [CAS]
150347-59-4 | [Synonyms]
CFSE CFDA SE NHS ester ≥90% (HPCE) 5(6)-FAM DA SE CFSE (CFDA-SE) -Cellstain-Cfse Vitamin B12-O5' 5-FAM-NHS DIACETATE 5(6)-CFDA N-succinmidyl ester 5-CARBOXYFLUORESCEIN-NHS DIACETATE Carboxyfluorescein succinimidyl ester CARBOXYFLUORESCEIN DIACETATE, NHS ESTER Cell proliferation tracer fluorescence probe 5(6)-CFDA (SE [5(6)-Carboxyfluorescein diacetate Carboxyfluorescein diacetate, succinimidyl ester 5-CARBOXY-FLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER 5-(6)-carboxy' Uorescein Diacetate Succinimidyl Ester 5-CARBOXY-DI-O-ACETYLFLUORESCEIN N-SUCCINIMIDYL ESTER 5(6)-carboxyfluorescein diacetate N-succinimidyl este 5(6)-CARBOXYFLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER 5-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXYSUCCINIMIDE ESTER 5(6)-Carboxyfluorescein diacetate, succinimidyl ester(CFDA) 5(6)-Carboxyfluorescein 3',6'-Diacetate N-SucciniMidyl Ester 5-or6-(N-Succinimidyloxycarbonyl)-fluorescein3',6'-diacetate 5(6)-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXY-SUCCINIMIDE ESTER 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN 5-or6-(N-Succiimidyloxycarbonyl)-3',6'-O,O'-diacethylfluorescein 3'',6''-O,O''-Diacetyl-5(6)-(N-succinimidyloxycarbonyl)-fluorescein 5(6)-CFDA, SE [5(6)-Carboxyfluorescein diacetate, succiniMidyl ester] 5-or 6-(N-Succinimidyloxycarbonyl)-3', 6'-O,O'-diacetylfluorescein (CFSE) 1-[[[3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]- Spiro[isobenzofuran-1(3h),9′-[9h]xanthene], 2,5-pyrrolidinedione derivative CFSE [5-(and 6)-Carboxyfluorescein diacetate, succinimidyl ester] *CAS 150347-59-4* ReadiUse CFSE [5-(and 6)-Carboxyfluorescein diacetate, succinimidyl ester] *CAS 150347-59-4* 2,5-Dioxopyrrolidin-1-ylacetatecompoundwith3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyldiacetate(1:1) 3',6'-Bis(acetyloxy)-3-oxo-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic Acid 2,5-Dioxo-1-pyrrolidinyl Ester Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylicacid, 3',6'-bis(acetyloxy)-3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C29H19NO11 | [MDL Number]
MFCD00037466 | [MOL File]
150347-59-4.mol | [Molecular Weight]
557.46 |
Chemical Properties | Back Directory | [Melting point ]
152-154 °C(lit.)
| [storage temp. ]
-20°C | [solubility ]
DMF: soluble
| [form ]
Solid | [pka]
6.45(at 25℃) | [color ]
Off-white to yellow | [PH Range]
Weak green ' uorescence (6.0) to strong green ' uorescence (7.2) | [λmax]
<300nm | [Major Application]
Diagnosis of cancer, restricting HIV replication, antiinflammatory agent, detecting bacteria, cell proliferation assays | [InChIKey]
QSWYNOQSGMUDQZ-UHFFFAOYSA-N |
Hazard Information | Back Directory | [Chemical Properties]
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN is Off-white to light yellow powder
| [Uses]
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN is a Non-fluorescent cell permeant amine-reactive probe for long term tracing of cell.
| [Uses]
A 5(6)-Carboxyfluorescein (C178215) derivative used as a flurorescent probe. 5(6)-Carboxyfluorescein 3’,6’-Diacetate N-Succinimidyl Ester is used to monitor lymphocyte proliferation by covalently labelling long-lived intracellular molecules with fluorescent dye. | [Uses]
Amine-reactive succinimidyl ester can potentially be used for long-term pH studies of live cells, producing a conjugate with the pH-sensitive properties of carboxyfluorescein. | [General Description]
5-(and-6)-Carboxyfluorescein diacetate N-succinimidyl ester (CFSE) is a fluorescent dye, which is membrane permeable. It labels cells by covalently binding to intracellular molecules. CFSE is used to track lymphocyte migration and proliferation. | [Biochem/physiol Actions]
5(6)-Carboxyfluorescein diacetate N-succinimidyl ester is used as an indicator for esterase activity. |
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