Identification | Back Directory | [Name]
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE | [CAS]
150145-89-4 | [Synonyms]
(S)-MCPG (+)-MCPG (alphaS)-alpha-Amino-4-Carbo (S)-α-Methyl-4-carboxyphenylglycine (+)-α-methyl-4-carboxyphenylglycine (S)-ALFA-METHYL-4-CARBOXYPHENYLGLYCINE (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE (+)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE 4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID (S)-alpha-Methyl-4-carboxyphenylglycine(S)-MCPG S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid 4-[(1S)-1-Ammonio-1-Methyl-2-Oxido-2-Oxoethyl]Benzoate 4-[(1S)-1-Ammonio-2-Keto-1-Methyl-2-Oxido-Ethyl]Benzoate 4-[(1S)-1-Azaniumyl-1-Methyl-2-Oxido-2-Oxo-Ethyl]Benzoate S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID (+-)-A-METHYL-4-CARBOXYPHENYLGLYCINE GLU TAMATE RECEPTOR AN (+)-MCPG, LY367385, S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid | [Molecular Formula]
C10H11NO4 | [MDL Number]
MFCD00216858 | [MOL File]
150145-89-4.mol | [Molecular Weight]
209.2 |
Chemical Properties | Back Directory | [Appearance]
white to off-white solid | [storage temp. ]
Store at RT | [solubility ]
0.1 M NaOH: 15 mg/mL
| [form ]
solid
| [color ]
White to off-white | [optical activity]
[α]20/D +89.54°, c = 0.33 in 6 M HCl(lit.) |
Hazard Information | Back Directory | [Chemical Properties]
white to off-white solid | [Biological Activity]
Active isomer of (RS)-MCPG ((RS)-a-Methyl-4-carboxyphenylglycine ). Non-selective group I/group II metabotropic glutamate receptor antagonist. Also available as part of the Group I mGlu Receptor Tocriset™ , Group II mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ . | [Uses]
Active enantiomer of (±)-MCPG | [Definition]
ChEBI: (S)-alpha-methyl-4-carboxyphenylglycine is a non-proteinogenic alpha-amino acid that is alanine in which the alpha-hydrogen is replaced by a 4-carboxyphenyl group (the S-enantiomer). It is a non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. It has a role as a metabotropic glutamate receptor antagonist. | [Biochem/physiol Actions]
(+)-α-Methyl-4-carboxyphenylglycine, also known as MCPG, is a competitive metabotropic glutamate receptor antagonist. | [storage]
Room temperature |
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BOC Sciences
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Sigma-Aldrich
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Musechem
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