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ChemicalBook--->CAS DataBase List--->1501-84-4

1501-84-4

1501-84-4 Structure

1501-84-4 Structure
IdentificationBack Directory
[Name]

Rimantadine hydrochloride
[CAS]

1501-84-4
[Synonyms]

jp61
exp126
meradan
ROFLUAL
MERADANE
FlumMine
FLUMADINE
remantadin
Remantadine
RIMANTADINE HCL
IFLAB-BB F1386-0449
TIMTEC-BB SBB003389
RAMANTADINE HYDROCHLORIDE
RIMANTADINE HYDROCHLORIDE
Remantadin(e)Hydrochloride
Flumadine, Meradane, Roflual
Rimantadine Hydrochloride (300 mg)
RiMantadine hydrochloride(FluMadine)
1-(1-Adamanty)ethylamine Hydrochloride
1-(1-aminoethyl)-adamantanhydrochloride
1-(1-ADAMANTYL)ETHANAMINE HYDROCHLORIDE
1-(1-ADAMANTYL)ETHYLAMINE HYDROCHLORIDE
1-(1-aminoethyl)adamantane hydrochloride
Rimantadine hydrochloride solution,100ppm
1-(1-AdaMantyl)ethylaMine hydrochloride 99%
1-(1-ADAMANTYL)ETHYLAMINE HYDROCHLORIDE 98+%
α-Methyl-1-adaman-tanemethylamine hydrochloride
α-Methyltricyclo[3.3.1.13,7]decane-1-MethanaMine
alpha-methyl-1-adamantanemethylaminhydrochloride
ALPHA-METHYL-1-ADAMANTANEMETHYLAMINE HYDROCHLORIDE
α-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Hydrochloride
a-Methyltricyclo[3.3.1.13,7]decane-1-methanamine Hydrochloride
Rimantadine hydrochloride Synonyms Flumadine
alpha-methyltricyclo(3.3.1.1(sup3,7))decane-1-methanaminehydrochloride
7))decane-1-methanamine,alpha-methyl-tricyclo(3.3.1.1(suphydrochloride
1-(Adamantan-1-yl)ethylamine hydrochloride, Rimantadine hydrochloride
alpha-Methyl-1-adamantanemethylamine Hydrochloride Rimantadine Hydrochloride
Tricyclo[3.3.1.13,7]decane-1-MethanaMine,a-Methyl-, hydrochloride (1:1)
[EINECS(EC#)]

604-725-9
[Molecular Formula]

C12H22ClN
[MDL Number]

MFCD00072023
[MOL File]

1501-84-4.mol
[Molecular Weight]

215.76
Chemical PropertiesBack Directory
[Appearance]

White Crystalline Solid
[Melting point ]

>300 °C(lit.)
[storage temp. ]

-20?C Freezer
[solubility ]

Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly), Water (Slig
[form ]

Solid
[color ]

White to Off-White
[Water Solubility ]

Freely soluble in water.
[Merck ]

8224
[InChI]

InChI=1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H
[InChIKey]

OZBDFBJXRJWNAV-UHFFFAOYSA-N
[SMILES]

C1C2CC3(C(N)C)CC1CC(C3)C2.Cl
[CAS DataBase Reference]

1501-84-4
Hazard InformationBack Directory
[Chemical Properties]

White Crystalline Solid
[Usage]

Used as an antiviral agent
[Description]

Rimantadine hydrochloride is an antiviral analogue of amantadine, reportedly useful in the prophylaxis and treatment of influenza A. Compared with amantadine, nmantadine appears to have a lower side-effect profile.
[Originator]

DuPont (USA)
[Uses]

Used as an antiviral agent
[Definition]

ChEBI: Rimantadine hydrochloride is an organic molecular entity.
[Brand name]

Flumadine (Forest);Roflual.
[storage]

Store at -20°C
[References]

[1] koff w c, elm jr j l, halstead s b. suppression of dengue virus replication in vitro by rimantadine hydrochloride[j]. the american journal of tropical medicine and hygiene, 1981, 30(1): 184-189.
[2] koff w c, peavy d l, knight v. inhibition of in vitro proliferative responses of human lymphocytes by rimantadine hydrochloride[j]. infection and immunity, 1979, 23(3): 665-669.
[3] hayden f g, monto a s. oral rimantadine hydrochloride therapy of influenza a virus h3n2 subtype infection in adults[j]. antimicrobial agents and chemotherapy, 1986, 29(2): 339-341.
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22-36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
[RTECS ]

AU4717000
[HS Code ]

29213000
[Toxicity]

LD50 oral in rat: 640mg/kg
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Lithium Aluminum Hydride-->Mercuric Oxide-->Vinyl bromide-->Adamantane-->RIMANTADINE HCL USP(CRM STANDARD)
Spectrum DetailBack Directory
[Spectrum Detail]

Rimantadine hydrochloride(1501-84-4)MS
Rimantadine hydrochloride(1501-84-4)1HNMR
Rimantadine hydrochloride(1501-84-4)13CNMR
Rimantadine hydrochloride(1501-84-4)IR1
Rimantadine hydrochloride(1501-84-4)IR2
Rimantadine hydrochloride(1501-84-4)Raman
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