| Identification | Back Directory | [Name]
RONGALITE | [CAS]
149-44-0 | [Synonyms]
aldanil
formapon
formopan
hydrolit
FORMOPON
FORMOSUL
Hydro AWC
discolite
rongalitc
RONGALITE
RONGALITE C
SFS-POWDER
hydrosulfiteawc
SFS-RICE GRADE
Rongalit dihydrate
formaldehydehydrosulfite
sodiummethanalsulfoxylate
sodiumoxymethanesulfinicacid
Natriumhydroxymethansulfinat
oxymethansulfinsaeurennatrium
SODIUM HYDROXYMETHANESULFINATE
SODIUMSULPHOXYLATEFORMALDEHYDE
SODIUM FORMALDEHYDESULFOXALATE
SODIUM FORMALDEHYDE SULFOXYLATE
SODIUM SULFOXYLATE FORMALDEHYDE
Sodiumbisulfoxylateformaldehyde
FORMALDEHYDE SODIUM SULFOXYLATE
sodium hydroxymethanesulphinate
formaldehydesodiumbisulfiteadduct
SodiuM HydroxyMethanesulfinate
formaldehydesulfoxylicacidsodiumsalt
Sodium hydroxymethanesulfinate hydrate
HYDROXYMETHANESULFINIC ACID SODIUM SALT
hydroxy-methanesulfinicacimonosodiumsalt
Sodium Formaldehyde Sulfoxylate, Pea Grade
Sodium Formaldehyde Sulfoxylate, Chip Grade
Methanesulfinicacid,hydroxy-,monosodiumsalt
Sodium Formaldehyde Sulfoxylate, Rice Grade
Sodium Formaldehyde Sulfoxylate, Powder Grade
Synonym Hydroxymethanesulfinic acid sodium salt
SodiuM hydroxyMethanesulfinate hydrate >=98.0% (RT)
sodium sulfoxylate formaldehyde：sodium fornaldehyde sulfoxylate
Formaldehyde Sodium Sulfoxylate
Hydroxymethanesulfinic Acid Sodium Salt
Rongalite
Hydroxymethanesulfinic acid sodium salt hydrate, 95% (dry wt.), cont, up to 5% sodium sulfite
HydroxyMethanesulfinic acid sodiuM salt hydrate, tech 85%, cont. up to 5% sodiuM sulfite (dry wt.)
Hydroxymethanesulfinic acid sodium salt, RongalitTM, Sodium formaldehyde sulfoxylate hydrate | [EINECS(EC#)]
205-739-4 | [Molecular Formula]
CH3NaO3S | [MDL Number]
MFCD00040426 | [MOL File]
149-44-0.mol | [Molecular Weight]
118.09 |
| Chemical Properties | Back Directory | [Appearance]
solid | [Melting point ]
~120 °C (dec.)
| [density ]
1.744[at 20℃] | [vapor pressure ]
0.003Pa at 20℃ | [Fp ]
>100℃ | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
H2O: 50 mg/mL, clear, colorless
| [form ]
Solid | [color ]
White to Off-White | [PH]
9.5-10.5 | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
soluble H2O, alcohol [HAW93] | [Merck ]
8620 | [EPA Substance Registry System]
Sodium sulfoxylate formaldehyde (anhydrous) (149-44-0) |
| Hazard Information | Back Directory | [Chemical Properties]
solid | [Uses]
Pharmaceutic aid (preservative). | [Production Methods]
Sodium formaldehyde sulfoxylate is manufactured from sodium
dithionate and formaldehyde in water. | [Purification Methods]
It crystallises from H2O as the dihydrate and decomposes at higher temperatures. Store it in a closed container in a cool place. It is insoluble in EtOH and Et2O and is a good reducing agent. [X-ray structure: Tuter J Chem Soc 3064 1955.] Note that this compound {HOCH2SO2Na} should not be confused with formaldehyde sodium bisulfite adduct {HOCH2SO3Na} from which it is prepared by reduction with Zn. [Beilstein 1 IV 3052.] | [Flammability and Explosibility]
Nonflammable | [Pharmaceutical Applications]
Sodium formaldehyde sulfoxylate is a water-soluble antioxidant
and is generally used as the dihydrate. It is used in the formulation
of injection products at a level of up to 0.1% w/v in the final
preparation administered to the patient. | [Safety]
The toxicological properties of sodium formaldehyde sulfoxylate
have not been fully investigated. However, it is used in the
formulation of injection products at a level to 0.1% w/v in the
final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by
ingestion, and when heated to decomposition it emits toxic fumes
of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg | [storage]
Store in well-closed, light-resistant containers at controlled room
temperature (15–30℃). | [Incompatibilities]
Sodium formaldehyde sulfoxylate is incompatible with strong
oxidizing agents; it is decomposed by dilute acid. | [Regulatory Status]
Included in the FDA Inactive Ingredients Database (parenteral
products up to 0.1% via the IM, IV, and SC routes). Included in the
Canadian List of Acceptable Non-medicinal Ingredients. |
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