Identification | Back Directory | [Name]
(R)-2-METHYLCYSTEINE HYDROCHLORIDE | [CAS]
148766-37-4 | [Synonyms]
α-Me-Cys-OH·HCl H-alpha-Me-L-Cys-OH*HCl 2-Methyl-D-cysteine HCl Alpha-Methyl-Cys-OH·HCl (R)-2-Methylcysteine HCl (R)-L-Α-METHYLCYSTEINE·HCL L-2-Methylcysteine hydrochloride 2-Methyl-L-cysteine Hydrochloride (R)-2-METHYLCYSTEINE HYDROCHLORIDE (R)-2-Methylcysteine hydrochloride, tech L-Cysteine, 2-Methyl-,hydrochloride (1:1) 2-Methyl-L-cysteine hydrochloride, 98% ee (R)-2-METHYLCYSTEINE HYDROCHLORIDE USP/EP/BP 2-Methyl-L-cysteine hydrochloride, 98%, 98% ee (R)-2-AMino-3-Mercapto-2-Methylpropanoic acid hydrochloride (R)-2-Amino-3-mercapto-2-methyl-propionic acid hydrochloride (2R)-2-Amino-2-methyl-3-sulfanyl-propanoic acid hydrochloride | [Molecular Formula]
C4H10ClNO2S | [MDL Number]
MFCD08063384 | [MOL File]
148766-37-4.mol | [Molecular Weight]
171.65 |
Chemical Properties | Back Directory | [Melting point ]
155-157℃ | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Methanol (Slightly), Water (Slightly) | [form ]
Powder | [color ]
White to pale yellow | [Stability:]
Hygroscopic |
Hazard Information | Back Directory | [Uses]
2-Methyl-?L-cysteine Hydrochloride is used in the preparation of isoteric thiazoline-oxazole largazole analogs which display cytoxicity. Also used in the synthesis of 2,3-diubstituted thiazoline for pharmaceutical synthesis. | [Application]
(R)-2-Methylcysteine hydrochloride is used as a pharmaceutical intermediate component in the synthesis of Largazole, a potent class I selective histone deacetylase (HDAC) inhibitor prodrug with anticancer activity against solid tumours in preclinical models. |
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