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ChemicalBook--->CAS DataBase List--->146943-43-3

146943-43-3

146943-43-3 Structure

146943-43-3 Structure
IdentificationBack Directory
[Name]

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester
[CAS]

146943-43-3
[Synonyms]

PeMetrexed Diethyl Ester
Pemetrexed Impurity 20(Pemetrexed Diethyl Ester)
(S)-Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,...
(S)-Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester
N-{4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-EL)ETHYL]BENZOYL}-L-GLUTAMIC?ACID?1,5-DIETHYL?ESTER
L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, 1,5-diethyl ester
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester USP/EP/BP
PeMetrexed diethyl ester (L-GlutaMic acid, N-[4-[2-(2-aMino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoyl]-, 1,5-diethyl ester )
[Molecular Formula]

C24H29N5O6
[MDL Number]

MFCD09833741
[MOL File]

146943-43-3.mol
[Molecular Weight]

483.52
Chemical PropertiesBack Directory
[Melting point ]

84-86 ºC
[density ]

1.38
[storage temp. ]

Refrigerator
[solubility ]

DMSO, Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

Pemetrexed Diethyl Ester is an protected intermediate in the synthesis of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes.
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