Identification | Back Directory | [Name]
PAPA NONOATE | [CAS]
146672-58-4 | [Synonyms]
NOC-15 PAPA/NO PAPA NONATE PAPA NONOATE NOC-15 NONOATE PROPYLAMINE PROPYLAMINE NONOATE 3-[[nitroso(oxido)amino]-propylamino]propylazanium 1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-PROPYL-1-TRIAZENE 3-(2-hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine 1-Propanamine, 3-(2-hydroxy-2-nitroso-1-propylhydrazinyl)- 3-(2-HYDROXY-2-NITROSO-1-PROPYLHYDRAZINO)-1-PROPANAMINE NONOATE 3-(2-Hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine, NOC-15 (Z)-1-[N-(3-AMINOPROPYL)-N-)B-PROPYL)AMINO]DIAZIN-1-IUM-1,2-DIOLATE (Z)-1-[N-(3-AMMONIOPROPYL)-N-(N-PROPYL)AMINO]DIAZEN-1-IUM-1,2-DIOLATE | [Molecular Formula]
C6H16N4O2 | [MDL Number]
MFCD00801020 | [MOL File]
146672-58-4.mol | [Molecular Weight]
176.22 |
Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
Soluble in Water or Ethanol. | [form ]
White to off-white solid. | [color ]
Off-white | [Stability:]
Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Solutions are not stable and must be prepared immediately before use. |
Hazard Information | Back Directory | [Description]
PAPA NONOate (146672-58-4) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of PAPA NONOate in 0.1 M phosphate buffer at pH 7.4 is 15 minutes at 37°C, or 77 minutes at room temperature.1?Dissociation is essentially instantaneous at a pH of 5.0. | [Uses]
PAPA NONOate is an NO donor which suppresses the caspase apoptotic cascade. | [Definition]
ChEBI: PAPA NONOate is an alkylamine. | [References]
1) Keefer?et al. (1996),?‘NONOates’ (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol.,?268?281 |
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Energy Chemical
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Resenbio
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