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ChemicalBook--->CAS DataBase List--->145918-75-8

145918-75-8

145918-75-8 Structure

145918-75-8 Structure
IdentificationBack Directory
[Name]

TROXACITABINE
[CAS]

145918-75-8
[Synonyms]

CS-150
L-Oddc
SPD 758
Troxatyl
(-)-Occc
Bch 4556
(-)-Bch 204
TROXACITABINE
α-L-Dioxolane-C
Lamivudine Impurity I
Troxacitabine (SGX-145)
Lamivudine EP Impurity I
Lamivudine Impurity I (Troxacitabine)
Lamivudine EP Impurity I (Troxacitabine)
4-Amino-1-[(2S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one
4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one
2(1H)-Pyrimidinone, 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)-
2(1H)-Pyrimidinone, 4-amino-1-(-2-(hydroxymethyl)-1,3-dioxolan-4-yl)-, (2S-cis)-
4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]-1,2-dihydropyrimidin-2-one
TROXACITABINE,2(1H)-PYRIMIDINONE, 4-AMINO-1-(2-(HYDROXYMETHYL)-1,3-DIOXOLAN-4-YL)-, (2S-CIS)-
[EINECS(EC#)]

200-258-5
[Molecular Formula]

C8H11N3O4
[MDL Number]

MFCD00871100
[MOL File]

145918-75-8.mol
[Molecular Weight]

213.19
Chemical PropertiesBack Directory
[Melting point ]

176-177°
[alpha ]

D25 -38.33° (c = 0.43 in MeOH).
[Boiling point ]

422.5±55.0 °C(Predicted)
[density ]

1.71±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

14.83±0.10(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

Troxacitabine is a nucleoside analogue with potential anticancer activity. Troxacitabine have been studied in patients with refractory lymphoproliferative diseases.
[Definition]

ChEBI: Troxacitabine is a nucleobase-containing molecular entity and a carbohydrate derivative.
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