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ChemicalBook--->CAS DataBase List--->1449240-68-9

1449240-68-9

1449240-68-9 Structure

1449240-68-9 Structure
IdentificationBack Directory
[Name]

K145 (hydrochloride)
[CAS]

1449240-68-9
[Synonyms]

K145(HCl)
SphK2 inhibitor
K14 (hydrochloride)
K145 (hydrochloride)
K145 hydrochloride >=98% (HPLC)
SPHK2 INHIBITOR;K 145 HYDROCHLORIDE;K-145 HYDROCHLORIDE
3-(2-Amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione hydrochloride
3-(2-Aminoethyl)-5-[3-(4-butoxyphenyl)propylidene]-2,4-thiazolidinedione hydrochloride (1:1)
[Molecular Formula]

C18H25ClN2O3S
[MDL Number]

MFCD28160629
[MOL File]

1449240-68-9.mol
[Molecular Weight]

384.921
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble20mg/mL, clear
[form ]

powder
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS05,GHS08
[Signal word ]

Danger
[Hazard statements ]

H315-H318-H334-H317-H341-H361-H370-H413
[Precautionary statements ]

P201-P202-P260-P264-P270-P272-P273-P280-P284-P302+P352-P304+P341-P305+P351+P338-P310-P308+P313-P321-P362+P364-P333+P313-P342+P311-P363-P405-P501
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

K145 hydrochloride has been used in the analysis of apoptosis.
[General Description]

K145 hydrochloride (3-(2-Amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione) is an analog of sphingosine.
[Biochem/physiol Actions]

It has the ability to prevent leukemia cell growth in vitro.
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