| Identification | Back Directory | [Name]
Y-29794 tosylate | [CAS]
143984-17-2 | [Synonyms]
Y-29794 tosylate
(2-((8-(dimethylamino)octyl)thio)-6-isopropylpyridin-3-yl)(thiophen-2-yl)methanone 4-methylbenzenesulfonate | [Molecular Formula]
C30H42N2O4S3 | [MDL Number]
MFCD30533391 | [MOL File]
143984-17-2.mol | [Molecular Weight]
590.86 |
| Hazard Information | Back Directory | [Description]
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor. Y-29794 selectively and competitively inhibited rat brain PPCE (Ki = 0.95 nM) in a reversible manner. Ex vivo study demonstrated that Y-29794 could penetrate into brain to exhibit dose-dependent and long-lasting inhibition. Furthermore, Y-29794 could potentiate the effect of TRH on the release of ACh in the rat hippocampus. Y-29794 prevents the progression of A beta-like deposition in the hippocampus of the SAM. |
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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