Identification | Back Directory | [Name]
1-Boc-azetidine-3-ylmethanol | [CAS]
142253-56-3 | [Synonyms]
EOS-61767 Boc-Azetidin-3-ylMethanol 1-Boc-3-(hydroxymethyl)az... 1-Boc-3-azetidinemethanol,95% 1-BOC-AZETIDINE-3-YL METHANOL 1-Boc-3-azetidineMethanol, 95% 1-N-Boc-3-hydroxyMethyazetidine 1-Boc-3-(hydroxymethyl)azetidine 1-Boc-3-(hydroxyMethyl)azetidine, 97+% 3-(Hydroxymethyl)azetidine-1-carboxylate 1-(tert-Butoxycarbonyl)-3-azetidineMethanol tert-butyl 2-(azetidin-3-yl)-2-hydroxyacetate 1-(tert-Butoxycarbonyl)-3-azetidinemethanol > TERT-BUTYL 3-(HYDROXYMETHYL)AZETIDINE-1-CARBOXYLATE 3-HYDROXYMETHYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-Azetidinecarboxylic acid, 3-(hydroxyMethyl)-, 1,1-diMethylethyl ester | [EINECS(EC#)]
218-697-7 | [Molecular Formula]
C9H17NO3 | [MDL Number]
MFCD06656141 | [MOL File]
142253-56-3.mol | [Molecular Weight]
187.24 |
Chemical Properties | Back Directory | [Melting point ]
55 °C | [Boiling point ]
268-273℃ | [density ]
1.115 | [Fp ]
117°(243°F) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Soluble in Dimethyl sulfoxide (DMSO). | [form ]
powder to lump | [pka]
14.82±0.10(Predicted) | [color ]
White to Almost white | [InChI]
InChI=1S/C9H17NO3/c1-9(2,3)13-8(12)10-4-7(5-10)6-11/h7,11H,4-6H2,1-3H3 | [InChIKey]
HXRDRJKAEYHOBB-UHFFFAOYSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CC(CO)C1 |
Hazard Information | Back Directory | [Description]
1-Boc-Azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). This compound is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
| [Chemical Properties]
Clear colorless liquid | [Uses]
It is an intermediate in organic syntheses |
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