| Identification | Back Directory | [Name]
SulfaMide, N-[5-(4-broMophenyl)-6-chloro-4-pyriMidinyl]-N'-propyl- | [CAS]
1393813-42-7 | [Synonyms]
Macitentan Impurity 16
Mecitentan Pyrimidine Amine Impurity
N-[5-(4-Bromphenyl)-6-chlorpyrimidin-4-yl]-N'-propylsulfamid
N-(5-(4-bromophenyl)-6-chloropyrimidin-4-yl)propane-1-sulfamide
N-[5-(4-bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propyl-Sulfa...
5-(4-bromophenyl)-6-chloro-N-(propylsulfamoyl)pyrimidin-4-amine
N-[5-(4-broMophenyl)-6-chloro-4-pyriMidinyl]-N'-propyl-SulfaMide
SulfaMide, N-[5-(4-broMophenyl)-6-chloro-4-pyriMidinyl]-N'-propyl- | [Molecular Formula]
C13H14BrClN4O2S | [MDL Number]
MFCD25372049 | [MOL File]
1393813-42-7.mol | [Molecular Weight]
405.7 |
| Chemical Properties | Back Directory | [Melting point ]
>185°C (dec.) | [Boiling point ]
518.2±60.0 °C(Predicted) | [density ]
1.612±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.75±0.50(Predicted) | [color ]
Pale Yellow |
| Hazard Information | Back Directory | [Uses]
N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N''-propylsulfamide is a useful synthetic intermediate in the synthesis of Macitentan (M105005); an orally active, potent dual endothelin receptor antagonist used for pulmonary arterial hypertension. |
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