| Identification | Back Directory | [Name]
Sineptina | [CAS]
1392-21-8 | [Synonyms]
c637
Ayermycin
Sineptina
Syneptine
ayermicina
Leucomycins
KITASAMYCIN
FORMACIDINE
selectomycin
Stereomycine
Leucomycin A1
Leucomycin hyd
Leucomycin Base
KITASAMYCIN BASE
LEUCOMYCIN HYDRATE
Leucomycin complex
Leucomycin (8CI, 9CI)
Acetylkitasamycin JPXIV | [EINECS(EC#)]
232-429-6 | [Molecular Formula]
C40H67NO14 | [MDL Number]
MFCD01314545 | [MOL File]
1392-21-8.mol | [Molecular Weight]
785.96 |
| Chemical Properties | Back Directory | [Melting point ]
128-145 °C | [storage temp. ]
2-8°C
| [solubility ]
ethanol: 50 mg/mL, clear to slightly hazy, light-yellow
| [form ]
neat | [color ]
White to Off-White | [Merck ]
14,5453 | [CAS DataBase Reference]
1392-21-8 |
| Hazard Information | Back Directory | [Usage]
Leucomycin complex (kitasamycin) is a family of closely related macrocyclic lactone antibiotics produced by Streptomyces kitasatoensis, discovered in 1953. The complex contained over 14 components with analogues A1, A4, A5, and A13 being the most abundant analogues. Leucomycin complex is used as an animal health product for control of Gram positive bacteria, Gram negative cocci, leptospira and mycoplasma. | [Description]
Kitasamycin, formerly called leucomycin, was found in the culture broth of Streptoverticillium kitasatoensis by Hata et al. of the Kitasato Institute, Japan, in 1953. This was the first macrolide antibiotic with a 16-membered lactone constituent. Kitasamycin is a complex of eight leucomycin A components and is used in its base and ester forms to treat gram-positive bacterial and gram-negative coccal infections, as well as infections of Mycoplasma, Spirochaeta, and Treponema by injection or by oral topical administration. | [Uses]
Leucomycins (>85%) (cas# 1392-21-8) is a compound useful in organic synthesis. | [Uses]
Sineptina is a family of closely related macrocyclic lactone antibiotics produced by Streptomyces kitasatoensis, discovered in 1953. The complex contained over 14 components with analogues A1, A4, A5, and A13 being the most abundant analogues.Sineptina is used as an animal health product for control of Gram positive bacteria, Gram negative cocci, leptospira and mycoplasma.
| [Definition]
ChEBI: Leucomycin V is a macrolide antibiotic produced by Streptomyces kitasatoensis, showing activity against a wide spectrum of pathogens. It has a role as a bacterial metabolite. It is a leucomycin and a macrolide antibiotic. | [Pharmaceutical Applications]
A naturally occurring product of Streptomyces kitasatoensis, available in Japan for parenteral and oral use, and as acetylkitasamycin for topical application. Elsewhere it is chiefly used in veterinary medicine. | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Safety Statements ]
24/25 | [WGK Germany ]
1
| [RTECS ]
WG9400000
| [F ]
10 | [HS Code ]
29419090 | [Toxicity]
mouse,LD50,intraperitoneal,1758mg/kg (1758mg/kg),Drugs in Japan Vol. -, Pg. 354, 1995. |
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