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ChemicalBook--->CAS DataBase List--->135729-78-1

135729-78-1

135729-78-1 Structure

135729-78-1 Structure
IdentificationBack Directory
[Name]

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
[CAS]

135729-78-1
[Synonyms]

Palonosetron Impurity 3
Palonosetron Impurity 20
Palonosetron Impurity 27
Palonosetron Impurity 25
Palonosetron Impurity 1
Palonosetron Intermediate
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetra
(S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxaMide
N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
(S)-N-1-azabicyclo[2.2.0]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxaMide
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
N-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl] 5,6,7,8-tetrahydronaphthalene-1-carboxamide
1-Naphthalenecarboxamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-
[Molecular Formula]

C18H24N2O
[MDL Number]

MFCD27923863
[MOL File]

135729-78-1.mol
[Molecular Weight]

284.4
Chemical PropertiesBack Directory
[Melting point ]

157-159oC
[density ]

1.17
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White
Hazard InformationBack Directory
[Uses]

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an impurity in the synthesis of Palonosetron HCl (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
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