| Identification | Back Directory | [Name]
Verinurad | [CAS]
1352792-74-5 | [Synonyms]
CS-2466
RDEA3170
HY-16733
Verinurad
Verinurad (RDEA3170)
2-[[3-(4-Cyano-1-naphthalenyl)-4-pyridinyl]thio]-2-methylpropanoic acid
2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid
Propanoic acid, 2-[[3-(4-cyano-1-naphthalenyl)-4-pyridinyl]thio]-2-methyl- | [Molecular Formula]
C20H16N2O2S | [MDL Number]
MFCD28963965 | [MOL File]
1352792-74-5.mol | [Molecular Weight]
348.42 |
| Chemical Properties | Back Directory | [Melting point ]
204 - 207°C | [Boiling point ]
566.7±50.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
2.91±0.10(Predicted) | [color ]
Off-White to Pale Brown |
| Hazard Information | Back Directory | [Description]
Verinurad is an inhibitor of urate anion transporter 1 (URAT1; IC50 = 0.025 μM for the human transporter). It is selective for human URAT1 over rat URAT1 (IC50 = 41 μM), as well as human organic anion transporter 1 (OAT1) and OAT4 (IC50s = 4.6 and 5.9 μM, respectively). | [Uses]
Verinurad is a second generation selective uric acid reabsorption inhibitor. |
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Jia Xing Isenchem Co.,Ltd
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