| Identification | Back Directory | [Name]
2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide | [CAS]
134742-26-0 | [Synonyms]
NSC639828
2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide
Benzamide, 2-amino-N-[[[4-[(5-bromo-2-pyrimidinyl)oxy]-3-chlorophenyl]amino]carbonyl]- | [Molecular Formula]
C18H13BrClN5O3 | [MOL File]
134742-26-0.mol | [Molecular Weight]
462.68 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C, protect from light | [solubility ]
DMSO : 100 mg/mL (216.13 mM; Need ultrasonic) | [form ]
Solid | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Biological Activity]
NSC639828 is a potent inhibitor of DNA polymerase α with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for researching cancer disease[1]. | [storage]
-20°C, protect from light | [References]
[1]. Abdel-Aziz W, et al. Effect of novel benzoylphenylurea derivatives on DNA polymerase alpha activity using the synthesome-based in vitro model system. Invest New Drugs. 2003;21(4):421-428. |
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