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ChemicalBook--->CAS DataBase List--->1345822-87-8

1345822-87-8

1345822-87-8 Structure

1345822-87-8 Structure
IdentificationBack Directory
[Name]

Sitagliptin EP Impurity B
[CAS]

1345822-87-8
[Synonyms]

4-Desfluoro Sitagliptin
Sitagliptin EP Impurity B
4-Desfluoro Sitagliptin Phosphate
Sitagliptin EP Impurity B Phosphate
Sitagliptin EP Impurity B / Sitagliptin 4-Desfluoro Impurity
(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,5-difluorophenyl)butan-2-amine phosphate
Sitagliptin impurity 3/Sitagliptin EP Impurity B/Sitagliptin 4-Desfluoro Impurity/(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,5-difluorophenyl)butan-2-amine phosphate
[Molecular Formula]

C16H19F5N5O5P
[MDL Number]

MFCD30747639
[MOL File]

1345822-87-8.mol
[Molecular Weight]

487.318
Chemical PropertiesBack Directory
[InChIKey]

UOKMPNRCGWVMBY-XAAIUDFWNA-N
[SMILES]

P(O)(O)(O)=O.C(N1CCN2C(C(F)(F)F)=NN=C2C1)(=O)C[C@H](N)CC1=CC(F)=CC=C1F |&1:21,r|
Hazard InformationBack Directory
[Uses]

4-Desfluoro Sitagliptin is a metabolite of Sitagliptin phosphate (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
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