| Identification | Back Directory | [Name]
EprinoMectin B1a | [CAS]
133305-88-1 | [Synonyms]
EprinoMectin B1a
Eprinomectin Component B
eprinomectin component B1a
ZKWQQXZUCOBISE-NAMFGXNGSA-N
Avermectin A1a, 4''-(acetylamino)-5-O-demethyl-4''-deoxy-, (4''R)- | [Molecular Formula]
C50H75NO14 | [MDL Number]
MFCD00866565 | [MOL File]
133305-88-1.mol | [Molecular Weight]
914.14 |
| Hazard Information | Back Directory | [Uses]
Eprinomectin B1a is a semi-synthetic analogue of avermectin B1a prepared by oxidation of the 4”-hydroxy moiety and reductive amination followed by acetylation. Eprinomectin B1a is the major component (>90%) of the commercial product for endo- and exo-parasite control, eprinomectin. Members of the avermectin/milbemycin class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides and acaricides. | [Definition]
ChEBI: An avermectin analogue that is avermectin A1a in which the methoxy group attached to the tetrahydrobenzofuranyl moiety is replaced by a hydroxy group and in which the hydroxy group at position 4 of the terminal 2,6-dideoxy-3-O
/element>-methyl-alpha-L-arabino-hyxopoyranosyl group is replaced by an acetamido group. | [Brand name]
Eprinex [Veterinary](Merial). | [storage]
Store at -20°C |
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