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ChemicalBook--->CAS DataBase List--->130580-02-8

130580-02-8

130580-02-8 Structure

130580-02-8 Structure
IdentificationBack Directory
[Name]

EPLIVANSERIN FUMARATE
[CAS]

130580-02-8
[Synonyms]

SR 46349B
SR-46349 Fumarate
EPLIVANSERIN FUMARATE
Eplivanserin hemifumarate
SR-46349 hemifumarate salt
Eplivanserin hemifumarate salt
SR-46349 hemifumarate salt >=98% (HPLC)
TRANS-2''-FLUORO-4-HYDROXYCHALCONE O-[(Z)-2-(DIMETHYLAMINO)ETHYL]OXIME--FUMARIC ACID (2:1)
4-((3Z)-3-(2-Dimethylaminoethyl)oxyimino-3-(2-fluorophenyl)propen-1-yl)phenol hemifumarate salt
(Z,E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime fumarate (2:1)
(1Z,2E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime hemifumarate
[Molecular Formula]

C23H25FN2O6
[MDL Number]

MFCD00893361
[MOL File]

130580-02-8.mol
[Molecular Weight]

444.46
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: ≥10mg/mL
[form ]

powder
[color ]

white to off-white
Safety DataBack Directory
[Hazard Codes ]

Xn,N
[Risk Statements ]

22-50
[Safety Statements ]

61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

2
Hazard InformationBack Directory
[Uses]

Eplivanserin Hemifumarate is a 5-HT2A antagonist.
[Biological Activity]

SR-46349 is an antagonist of 5-HT (2A/2C) receptor and increases the release of dopamine by medial prefrontal cortex in rats.1 It increases the signal transduction induced by 5-HT2 receptor by binding with high affinity.2 SR-46349 inhibits the aggregation of rabbit and human platelets in response to serotonin.3''ASTAR (Antagonist of Serotonin 5HT2A Receptors).
[storage]

Store at +4°C
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