| Identification | Back Directory | [Name]
QUININE HCL | [CAS]
130-89-2 | [Synonyms]
QUININE HCL
chinimetten
quininemuriate
quininechloride
QUININE HYDROCHLORIDE
Quinine HCL & Sulfate
Hydrochloric acid quinine
Quinine·hydrochloric acid
QUININE MONOHYDROCHLORIDE
QUININE HYDROCHLORIDE 2 H2O
Quinine, monohydrochloride (8CI)
(8alpha,9R)-6'-methoxycinchonan-9-ol monohydrochloride
6’-methoxy-,monohydrochloride,(8-alpha,9r)-cinchonan-9-o
6’-methoxy-,monohydrochloride,(8.alpha.,9R)-Cinchonan-9-ol
6’-methoxy-,monohydrochloride,(8alpha,9theta)-cinchonan-9-o
Cinchonan-9-ol, 6-methoxy-, monohydrochloride, (8.alpha.,9R)-
Cinchonan-9-ol,6'-Methoxy-, hydrochloride (1:1), (8alpha,9R)-
Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, (8a,9R)- (9CI)
(R)-[(4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol:hydrochloride | [EINECS(EC#)]
205-001-1 | [Molecular Formula]
C20H25ClN2O2 | [MDL Number]
MFCD00078498 | [MOL File]
130-89-2.mol | [Molecular Weight]
360.88 |
| Chemical Properties | Back Directory | [Melting point ]
158-160 C | [density ]
1.1206 (rough estimate) | [FEMA ]
2976 | QUININE HYDROCHLORIDE | [refractive index ]
1.5400 (estimate) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Ethanol (Slightly) | [form ]
Solid | [color ]
White | [Water Solubility ]
549.7mg/L(25 ºC) | [InChIKey]
LBSFSRMTJJPTCW-QJLYHTAINA-N | [SMILES]
C12C=C(C=CC=1N=CC=C2[C@@H](O)[C@]1([H])C[C@]2([H])CCN1C[C@@H]2C=C)OC.Cl |&1:10,12,15,21,r| | [LogP]
3.496 (est) | [EPA Substance Registry System]
Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8.alpha.,9R)- (130-89-2) |
| Hazard Information | Back Directory | [Chemical Properties]
silky needles | [Uses]
Quinine Hydrochloride is an antimalarial drug. | [Definition]
Quinine Hydrochloride is the hydrochloride of a natural substance, quinine, obtained from the bark of various species of Cinchona including Cinchona succirubra, Pavon. (red cinchona); Cinchona officinalis, Linn; Cinchona calizaya, Wenddell; Cinchona ledgeriana, Moens. It is a nature-derived bitter flavoring agent for tonic water, among other beverages. | [Biological Activity]
Quinine hydrochloride is a displays antimalarial and muscle relaxant properties. Stereoisomer of quinidine; closely related to chloroquine.? | [Synthesis]
Manufacture of quinine by extraction from Cinchona bark and subsequent purification and synthesis to quinine hydrochloride. | [target]
Adrenergic Receptor | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36-24/25 | [RIDADR ]
1544 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29392000 | [Safety Profile]
Poison by ingestion, subcutaneous, intravenous, intramuscular, and intraperitoneal routes. Human systemic effects by intravenous route: convulsions or effect on seizure threshold, muscle contraction or spasticity, and nausea or vomiting. Mutation data reported. Used as a local anesthetic. When heated to decomposition it emits very toxic fumes of NO, and HCI. See also QUININE. | [Toxicity]
cat,LDLo,intravenous,80mg/kg (80mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 327, 1927. |
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