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ChemicalBook--->CAS DataBase List--->129558-76-5

129558-76-5

129558-76-5 Structure

129558-76-5 Structure
IdentificationBack Directory
[Name]

TOLFENPYRAD
[CAS]

129558-76-5
[Synonyms]

omi-88
HATI-HATI
TOLFENPYRAD
TOLFENPYRAD STANDARD
tolfenpyrad (bsi, pa iso)
4-Chloro-3-ethyl-1-methyl-N-[4-(p-tolyloxy)benzyl]pyrazole-5-carboxamide
4-chloro-3-ethyl-1-Methyl-N-(4-(p-tolyloxy)benzyl)-1H-pyrazole-5-carboxaMide
4-Chloro-3-ethyl-1-methyl-N-{[4-(4-methylphenoxy)phenyl]methyl}-1H-pyrazole-5-carboxamide
1H-Pyrazole-5-carboxaMide, 4-chloro-3-ethyl-1-Methyl-N-[[4-(4-Methylphenoxy)phenyl]Methyl]-
[Molecular Formula]

C21H22ClN3O2
[MDL Number]

MFCD08273850
[MOL File]

129558-76-5.mol
[Molecular Weight]

383.87
Chemical PropertiesBack Directory
[Melting point ]

87~89℃
[Boiling point ]

540.0±50.0 °C(Predicted)
[density ]

1.21±0.1 g/cm3(Predicted)
[storage temp. ]

0-6°C
[solubility ]

Chloroform (Slightly), DMSO (Slightly)
[form ]

neat
[pka]

13.11±0.46(Predicted)
[color ]

White to off-white
[BRN ]

13666608
[InChIKey]

WPALTCMYPARVNV-UHFFFAOYSA-N
[CAS DataBase Reference]

129558-76-5
[EPA Substance Registry System]

1H-Pyrazole-5-carboxamide, 4-chloro-3-ethyl-1-methyl-N-[[4-(4-ethylphenoxy)phenyl]methyl]- (129558-76-5)
Hazard InformationBack Directory
[Uses]

Tolfenpyrad
[Definition]

ChEBI: An aromatic amide obtained by formal condensation of the carboxy group of 4-chloro-3-ethyl-1-methylpyrazole-5-carboxylic acid with the amino group of 1-[4-(4-methylphenoxy)phenyl]methylamine.
[storage]

Store at -20°C
Safety DataBack Directory
[Hazard Codes ]

Xn,N
[Risk Statements ]

20/22-50/53
[Safety Statements ]

60-61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

3
Questions And AnswerBack Directory
[Description]

Tolfenpyrad is a pyrazole insecticide developed by Mitsubishi Chemical. It was first approved in 2002 in Japan under the trade name of Hachi-hachi.
It has broad insecticidal activity against a variety of pests such as Hemiptera, Coleoptera, Diptera, Lepidoptera, Thysanoptera and Acarina. It is especially effective against pests that are resistant to existing insecticides such as organophosphates and carbametes, because it supposedly possesses a new mode of action: inhibition of Complex I in the respiratory electron-transfer chain of mitochondria. It is applied for vegetables particularly cruciferous leafy varieties, cucurbits, cole crops, tea, fruits & nuts, selected row crops, and indoor ornamentals except cut flowers.
[References]

[1] http://sitem.herts.ac.uk/aeru/iupac/Reports/1687.htm  
[2] Koji Yamaguchi,  Wakako Hikiji, Masahiko Takino, Kanju Saka, Makiko Hayashida, Tatsushige Fukunaga, Youkichi Ohno (2012) Analysis of Tolfenpyrad and its Metabolites in Plasma in a Tolfenpyrad Poisoning Case, 36, 529-537
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