| Identification | Back Directory | [Name]
1,3-DIBROMO-5-TERT-BUTYLBENZENE | [CAS]
129316-09-2 | [Synonyms]
1,3-DibroMo-5-t-butylbenzene
3,5-DibroMo tert-butylbenzene
3-DIBROMO-5-TERT-BUTYLBENZENE
1,3-DIBROMO-5-TERT-BUTYLBENZENE
5-(tert-Butyl)-1,3-dibromobenzene
1,3-dibromo-5-(1,1-dimethylethyl)-Benzene
Benzene, 1,3-dibromo-5-(1,1-dimethylethyl)-
3,5-dibromo-t-butylbenzene,5-tert-butyl-1,3-dibromobenzene,3,5-dibromo-1-tert-butylbenzene,1,3-dibromo-5-(tert-butyl)benzene,1,3-Dibromo-5-t- | [Molecular Formula]
C10H12Br2 | [MDL Number]
MFCD06657956 | [MOL File]
129316-09-2.mol | [Molecular Weight]
292.01 |
| Chemical Properties | Back Directory | [Boiling point ]
250.0±20.0 °C(Predicted) | [density ]
1.549±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Pale Brown |
| Hazard Information | Back Directory | [Uses]
1,3-dibromo-5-tert-butylbenzene is a versatile building block that can be used to create a range of compounds. | [Application]
To a stirring solution of 1,3-dibromo-5-tert-butylbenzene (5.0 g, 17.0 mmol) in dry ether at ?78°C, n-Butyllithium (1.1 equiv.) was added dropwise. After stirring for 30 min under the N2 atmosphere, N-methoxy-N-methylacetamide (2.4 ml, 22.1 mmol) was added dropwise. The reaction mixture was allowed to warm to room temperature and stirred for 12 h. After quenching with a saturated solution of ammonium chloride, water was added, and the mixture was extracted with ether (2 × 150 ml). The combined organic extracts were washed with water (2 × 200 ml), dried with MgSO4 and evaporated to give a crude product. Purification was done by silica gel flash column chromatography using ethyl acetate: n-hexane mixture (v:v = 1:28) as eluent to give 1-(3-bromo-5-(tert-butyl)phenyl)ethanone as pale yellow oil. |
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