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ChemicalBook--->CAS DataBase List--->129273-26-3

129273-26-3

129273-26-3 Structure

129273-26-3 Structure
IdentificationBack Directory
[Name]

DIGOXIGENIN NHS-ESTER
[CAS]

129273-26-3
[Synonyms]

5'-Digoxin Phosphoramidite
Digoxigenin NHS-ester >=80% (HPLC)
-aminocaproic acid-N-hydroxysuccinimide ester
ω-(Digoxigenin-3-0-acetamido)caproic acid N-hydroxysuccinimide ester
n-hydroxysuccinimidyldigoxigenin-3-o-methylcarbonyl-epsilon-aminocaproate
Digoxigenin-3-O-methylcarbonyl-ε-aminocaproic acid-N-hydroxysuccinimide ester
(3β,5β,12β)-3-[2-[[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]amino]-2-oxoethoxy]-12,14-dihydroxycard-20(22)-enolide
[Molecular Formula]

C35H50N2O10
[MDL Number]

MFCD02093394
[MOL File]

129273-26-3.mol
[Molecular Weight]

658.784
Chemical PropertiesBack Directory
[density ]

1.33±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

DMF: soluble
[form ]

powder
[pka]

14.43±0.70(Predicted)
[Stability:]

Moisture Sensitive
Safety DataBack Directory
[Hazard Codes ]

T+
[Risk Statements ]

26/27/28-33
[Safety Statements ]

28-36/37-45
[RIDADR ]

UN 2811 6.1/PG 1
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Digoxigenin NHS-ester is an activated ester which reacts with amino groups under mild conditions, attaching the digoxigenin moiety to proteins or 5′-amino substituted oligonucleotides Digoxigenin labeling is used to immuno-tag molecules for detection using anti-digoxigenin antibodies with high affinities and specificity.
[Uses]

Digoxigenin-3-O-methylcarbonyl-ε-aminocaproic acid-N-hydroxysuccinimide ester has been used to label the sequence (III) for the linker molecule sequence (VIII).
[General Description]

Chemical reagent for the labeling of proteins and oligonucleotides. One reactive group is able to interact with NH2-groups (of proteins or oligonucleotides), another reactive group (Digoxigenin) reacts with Anti-Digoxigenin and thus can be detected.
[Biochem/physiol Actions]

Digoxigenin, a non-radioactive immune-tag is mainly used for labeling proteins and in situ?hybridization.
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