Identification | Back Directory | [Name]
beta-Cyclodextrin methyl ethers | [CAS]
128446-36-6 | [Synonyms]
MBC MEBCD Me-β-CD BETA-CYD RM-β-CD-o BETA-W7 M1.8 Cavasol? W7 M Cavasol? W7 M PH Methyl-?cyclodextrin METHYL B-CYCLODEXTRIN Methylophioponanone B METHYL-SS-CYCLODEXTRIN Dimethyl-β-Cyclodextrin METHYL-BETA-CYCLODEXTRIN Methylated-B-cyclodextrin Methylated-β-Cyclodextrin B-Cyclodextrin methyl ether β-Cyclodextrin methyl ethers Methyl-beta-cyclodextrin  (Mixture of several Methylated) .beta.-cyclodextrin,methylethers Methyl-beta-cyclodextrin(Me-β-CD) Randomly methylated-β-Cyclodextrin Methyl-β-cyclodextrin [average M.W. 1310] methyl-B-cyclodextrin cell culture*tested Methyl-beta-cyclodextrin,average Mn ~1310 METHYL-B-CYLODEXTRIN NON-TOXIC SOLUBILIZ ER Methyl-Beta-cyclodextrin=Cyclodextrinmethyle Methyl-β-cyclodextrin, Average Mn approx. 1310 (RANDOM) METHYL BETA CYCLODEXTRIN,*TECHNICAL GRADE (RANDOM) METHYL BETA-CYCLODEXTRIN,*PHARMACEUTICAL G methyl-β-cyclodextrin cyclomaltoheptaose, methylether Methyl-β-cyclodextrin (Mixture of several Methylated) Methyl-beta-cyclodextrin (mixture of several Methylated) Methyl-beta-cyclodextrin Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, >=98.0% cyclodextrin basis | [EINECS(EC#)]
1308068-626-2 | [Molecular Formula]
C54H94O35 | [MDL Number]
MFCD00074980 | [MOL File]
128446-36-6.mol | [Molecular Weight]
1303.3 |
Chemical Properties | Back Directory | [Appearance]
White powder | [Melting point ]
180-182 °C(lit.)
| [alpha ]
+159°(25℃, c=1, H2O) | [Fp ]
187 °C | [storage temp. ]
room temp | [solubility ]
H2O: soluble50mg/mL | [form ]
powder
| [color ]
White to off-white | [optical activity]
[α]25/D +159°, c = 1 in H2O | [Water Solubility ]
Soluble in water | [InChIKey]
YZOUYRAONFXZSI-SBHWVFSVSA-N | [LogP]
-2.566 (est) | [EPA Substance Registry System]
.beta.-Cyclodextrin, methyl ethers(128446-36-6) |
Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
substrate for laminarinase and other glucanases | [Description]
Methyl-β-cyclodextrin is a randomly methylated form of the cyclic oligosaccharide β-cyclodextrin (Item No. 23387).1 Methyl-β-cyclodextrin contains seven D-(+)-glucopyranose units that contain randomized hydrogen or methyl groups. Methyl-β-cyclodextrin has been used to improve the aqueous solubility of various compounds and to extract cholesterol from lipid membranes.1,2 Methyl-β-cyclodextrin (5 mM) reduces α-synuclein levels in the membrane and detergent-insoluble fractions from B103 neuroblastoma cells transfected with human α-synuclein.3 It also reduces α-synuclein levels in mouse brain in a transgenic model of α-synucleinopathy. | [General Description]
Methyl-β-cyclodextrin is a small cyclic heptasaccharide. | [Biochem/physiol Actions]
Methyl-β-cyclodextrin participates in increasing the permeability of cells. It also plays a role in depolymerizing the actin cytoskeleton in cells. Methyl-β-cyclodextrin is involved in attracting cholesterol from the plasma. It participates in activating extracellular receptor kinase in certain cells. |
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