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ChemicalBook--->CAS DataBase List--->125743-80-8

125743-80-8

125743-80-8 Structure

125743-80-8 Structure
IdentificationBack Directory
[Name]

Loratadine EP IMpurity F
[CAS]

125743-80-8
[Synonyms]

Fluoroloratadine
Loratadine EP IMpurity F
OVPFJWGOZPZTKG-UHFFFAOYSA-N
11-Fluoro Dihydroloratadine
Ethyl 4-[(11RS)-8-Chloro-11-fluoro-
Loratadine Impurity 4/Loratadine EP Impurity F
Loratadine Impurity 6(Loratadine EP Impurity F)
Ethyl 4-((11RS)-8-chloro-11-fluoro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidi
ethyl 4-(8-chloro-11-fluoro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate
Ethyl 4-[(11RS)-8-chloro-11-fluoro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate
1-Piperidinecarboxylic acid, 4-( 8-chloro-11-fluoro-6,11-dihydro -5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-, ethyl ester
[Molecular Formula]

C22H24ClFN2O2
[MDL Number]

MFCD00672869
[MOL File]

125743-80-8.mol
[Molecular Weight]

402.89
Chemical PropertiesBack Directory
[Melting point ]

149-153 °C
[Boiling point ]

490.3±45.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[form ]

neat
[pka]

3.65±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Loratadine Impurity F (Loratadine EP Impurity F; Loratadine USP Related Compound G Impurity) is a fluorinated analog of Loratadine (L469575), which is a nonsedating-type histamine H1-receptor.
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