Identification | Back Directory | [Name]
15-Azido-4,7,10,13-tetraoxapentadecanoic acid | [CAS]
1257063-35-6 | [Synonyms]
N3-Peg(4)-cooh Azido-PEG4-acid Azido-PEG5-acid N3-PEG4-CH2CH2COOH Azido-PEG4-C2-acid Azido-dPEG(R)4-acid Azido-PEG4-propionic acid Azido-PEG4-C2-carboxylic Acid 15-Azido-4,7,10,13-tetraoxapentadecanoic acid 1-Azido-3,6,9,12-tetraoxapentadecan-15-oic Acid 15-Azido-4,7,10,13-tetraoxapentadecanoic acid≥ 97% (NMR) 3-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid | [Molecular Formula]
C11H21N3O6 | [MDL Number]
MFCD12406155 | [MOL File]
1257063-35-6.mol | [Molecular Weight]
291.301 |
Hazard Information | Back Directory | [Description]
Azido-PEG4-acid is a very popular PEG reagent containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Chemical Properties]
Light yellow to colorless thick liquid | [Uses]
Azido-PEG4-Acid is amine- or phosphine-reactive building block used to derivative primary amines for ligation to alkyne-tagged molecules. |
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