| Identification | Back Directory | [Name]
(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride | [CAS]
125572-93-2 | [Synonyms]
(6S)-
CS-1395
rotigotine HCl
Rotigotine hydrochloride
hydrochloride hcl powder
CEXBONHIOKGWNU-NUDVEOEASA-N
[2H3]-Rac Rotigotine Hydrochloride Salt
8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]aMino]-
(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
(S)-6-(propyl(2-(thiophen-2-yl)ethyl)aMino)-5,6,7,8-tetrahydronaphthalen-1-ol
(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenolhydrochloride
(S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol hydrochloride
(S)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride
1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]aMino]-, hydrochloride, (6S)-
1-Naphthalenol,5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]aMino]-, hydrochloride (1:1),(6S)- | [EINECS(EC#)]
603-080-0 | [Molecular Formula]
C19H26ClNOS | [MOL File]
125572-93-2.mol | [Molecular Weight]
351.93 |
| Chemical Properties | Back Directory | [Melting point ]
114-117°C | [density ]
1.2g/cm3 at 20℃ | [vapor pressure ]
0-0Pa at 20-25℃ | [storage temp. ]
room temp | [solubility ]
Acetone (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly) | [form ]
solid | [color ]
white to off-white | [Stability:]
Hygroscopic | [LogP]
3.1 at 20℃ and pH7 | [Surface tension]
72.3mN/m at 1g/L and 20℃ |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease. | [Biochem/physiol Actions]
Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist. | [storage]
Store at -20°C |
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