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ChemicalBook--->CAS DataBase List--->124900-72-7

124900-72-7

124900-72-7 Structure

124900-72-7 Structure
IdentificationBack Directory
[Name]

YM17E
[CAS]

124900-72-7
[Synonyms]

YM17E
Urea, N,N''-[1,3-phenylenebis(methylene)]bis[N-cycloheptyl-N'-[4-(dimethylamino)phenyl]- (9CI)
[Molecular Formula]

C40H56N6O2
[MOL File]

124900-72-7.mol
[Molecular Weight]

652.91
Chemical PropertiesBack Directory
[Boiling point ]

862.7±65.0 °C(Predicted)
[density ]

1.16±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

14.03±0.70(Predicted)
[color ]

White to off-white
Spectrum DetailBack Directory
[Spectrum Detail]

YM17E(124900-72-7)1HNMR
Hazard InformationBack Directory
[Biological Activity]

YM17E is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) with IC50 of 44 nM in vitro in rabbit liver microsomes.
[in vitro]

YM17E is as potent in inhibiting ACAT activity in the liver as in the intestine, with IC 50 values of 45 and 34 nM, respectively.

[target]

IC50: 44 nM (ACAT in rabbit liver microsomes)

[storage]

Store at -20°C
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