Identification | Back Directory | [Name]
N-desMethyl EnzalutaMide | [CAS]
1242137-16-1 | [Synonyms]
CS-1325 N-desmethyl MDV3100 N-desmethyl MDV-3100 N-desmethyl MDV 3100 Enzalutamide Impurity R Enzalutamide impurity O Enzalutamide impurity B Enzalutamide Impurity 2 N-desMethyl EnzalutaMide Enzaluramide Impurities 2? Enzalutamide N-Desmethyl Impurity N-desmethyl MDV3100, N-desmethyl-Enzalutamide N-DESMETHYL MDV3100;N-DESMETHYL MDV 3100;N-DESMETHYL MDV-3100 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluorobenzaMide Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro- | [Molecular Formula]
C20H14F4N4O2S | [MDL Number]
MFCD24386671 | [MOL File]
1242137-16-1.mol | [Molecular Weight]
450.41 |
Chemical Properties | Back Directory | [Melting point ]
>230oC (dec.) | [storage temp. ]
Amber Vial, Refrigerator | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Light Sensitive |
Hazard Information | Back Directory | [Uses]
N-desMethyl EnzalutaMide is used in the treatment of disorders involving androgen, estrogen and progesterone receptors.
| [Definition]
ChEBI: N-desmethylenzalutamide is a benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with ammonia. It has a role as an antineoplastic agent and an androgen antagonist. It is a member of benzamides, an imidazolidinone, a nitrile, a thiocarbonyl compound, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes. |
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