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ChemicalBook--->CAS DataBase List--->1241675-76-2

1241675-76-2

1241675-76-2 Structure

1241675-76-2 Structure
IdentificationBack Directory
[Name]

(R)-DRF053 dihydrochloride
[CAS]

1241675-76-2
[Synonyms]

DRF053
DRF 053
[Molecular Formula]

C23H28ClN7O
[MOL File]

1241675-76-2.mol
[Molecular Weight]

453.98
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble to 100 mM in water and to 100 mM in DMSO
[form ]

Powder
Hazard InformationBack Directory
[Description]

Potent, ATP-competitive inhibitor of cyclin-dependent kinase (cdk) and casein kinase 1 (CK1) (IC50values are 220, 80 and 14 nM for cdk1/cyclin B, cdk5/p25 and CK1 respectively). Selective over GSK-3αβ(IC50= 4.1μM). Also shown to inhibit amyloid-βproduction in N2A-APP695cells.
[Uses]

(R)-DRF053 DiHydrochloride (cas# 1241675-76-2) is a useful research chemical.(R)-DRF053 Dihydrochloride was used for studying cancer treatments using combinations of CDK kinase and ERK inhibitors.
[storage]

Store at -20°C
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