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ChemicalBook--->CAS DataBase List--->1225-55-4

1225-55-4

1225-55-4 Structure

1225-55-4 Structure
IdentificationBack Directory
[Name]

PROTRIPTYLINE HYDROCHLORIDE
[CAS]

1225-55-4
[Synonyms]

mk-240
maximed
concordin
normethylex4442
PROTRIPTYLINE HCL
triptilhydrochloride
Protriptylin hydrochloride
PROTRIPTYLINE HYDROCHLORIDE
Protriptyline HCl, 1.0 mg/mL
Protriptyline Hydrochloride (200 mg)
Protriptyline hydrochloride solution
d)cyclohepten-5-propylamine,n-methyl-5h-dibenzo(hydrochloride
n-methyl-5h-dibenzo(a,d)cycloheptene-5-propylaminehydrochloride
5-(3-methylaminopropyl)-5h-dibenzo(a,d)cycloheptenehydrochloride
N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine hydrochloride
5H-Dibenzo[A,D]cyclohepten-5-propylamine, N-methyl-, hydrochloride
5H-Dibenzo[A,D]cycloheptene-5-propanamine, N-methyl-, hydrochloride
5H-Dibenzo[A,D]cycloheptene-5-propylamine, N-methyl-, hydrochloride
3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-Methylpropan-1-aMine hydrochloride
[EINECS(EC#)]

214-956-3
[Molecular Formula]

C19H22ClN
[MDL Number]

MFCD00072057
[MOL File]

1225-55-4.mol
[Molecular Weight]

299.84
Chemical PropertiesBack Directory
[Melting point ]

169-171°
[Fp ]

9℃
[storage temp. ]

2-8°C
[solubility ]

H2O: soluble50mg/mL
[form ]

powder
[pka]

8.2(at 25℃)
[color ]

white to off-white
[Water Solubility ]

H2O: 50mg/mL
[Stability:]

Hygroscopic
Safety DataBack Directory
[Hazard Codes ]

Xn,T,F
[Risk Statements ]

20/21/22-36/37/38-39/23/24/25-23/24/25-11
[Safety Statements ]

26-36-45-36/37-16-7
[RIDADR ]

3249
[WGK Germany ]

3
[RTECS ]

HP1400000
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[HS Code ]

2921490002
[Toxicity]

dog,LDLo,oral,400mg/kg (400mg/kg),"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 88, 1972.
Hazard InformationBack Directory
[Uses]

Monoamine reuptake inhibitor; tricyclic antidepressant.
[Brand name]

Vivactil (Odyssey).
[General Description]

Protriptyline hydrochloride, N-methyl-5H-dibenzo[a,d]-cycloheptene-5-propylamine hydrochloride, 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene hydrochloride(Vivactil), like the other compounds under consideration, isan effective antidepressant. The basis for its chemical namingcan be seen by consulting the naming and the structureof imipramine. Protriptyline is a structural isomer of nortriptyline.Inactivation can be expected to involve the relativelylocalized double bond. Because it is a monomethylcompound, its sedative potential is low.
[Biochem/physiol Actions]

Norepinephrine uptake blocker.
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