| Identification | Back Directory | [Name]
Delpazolid | [CAS]
1219707-39-7 | [Synonyms]
CS-2617
Delpazolid
LCB01-0371
Delpazolid (LCB01-0371)
DELPAZOLID; LCB01-0371; LCB 01-0371; LCB-01-0371; LCB010371; LCB 010371; LCB-010371
(R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
(5R)-3-[4-(5,6-Dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone
2-Oxazolidinone, 3-[4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-, (5R)-
Delpazolid/(5R)-3-[4-(5,6-Dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone | [Molecular Formula]
C14H17FN4O3 | [MDL Number]
MFCD29918770 | [MOL File]
1219707-39-7.mol | [Molecular Weight]
308.31 |
| Chemical Properties | Back Directory | [Boiling point ]
481.8±55.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:30.0(Max Conc. mg/mL);97.3(Max Conc. mM) | [form ]
A crystalline solid | [pka]
14.05±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Delpazolid is an oxazolidinone antibiotic.1 It is active against a wide range of Gram-positive bacterial clinical isolates, including resistant strains of several species, such as methicillin-resistant S. aureus (MRSA), methicillin-resistant coagulase-negative staphylococci (MRCNS), and penicillin-resistant S. pneumoniae (MICs = 0.125-4 μg/ml). Delpazolid increases survival in mouse models of systemic MRSA, E. faecalis, S. pneumoniae, and H. influenzae infection (ED50s = 2.96, 4.53, 2.28, and 9.96 mg/kg, respectively). | [storage]
Store at -20°C |
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| Company Name: |
Twochem Co.Ltd
|
| Tel: |
021-021-58111628 15800915896 |
| Website: |
www.twochem.com |
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