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ChemicalBook--->CAS DataBase List--->121577-32-0

121577-32-0

121577-32-0 Structure

121577-32-0 Structure
IdentificationBack Directory
[Name]

Gatifloxacinacid
[CAS]

121577-32-0
[Synonyms]

Gatifloxacinacid
AM 1155 hydrochloride
PD 135432 hydrochloride)
BMS-206584 (hydrochloride)
BMS 206584-01 hydrochloride
Gatifloxacin hydrochloride (AM 1155 hydrochloride
AM 1155 HYDROCHLORIDE;BMS 206584-01 HYDROCHLORIDE;PD 135432 HYDROCHLORIDE
3-Quinolinecarboxylicacid,1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-,hydrochloride (1:1)
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-, Monohydrochloride (9CI)
[Molecular Formula]

C19H22FN3O4.ClH
[MOL File]

121577-32-0.mol
[Molecular Weight]

411.859
Chemical PropertiesBack Directory
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

Soluble in DMSO
[form ]

Powder
[color ]

White to off-white
Spectrum DetailBack Directory
[Spectrum Detail]

Gatifloxacinacid(121577-32-0)1HNMR
Hazard InformationBack Directory
[Biological Activity]

Gatifloxacin hydrochloride (AM-1155 hydrochloride) is a potent fluoroquinolone antibiotic with broad-spectrum antimicrobial activity.
[in vivo]

Gatifloxacin hydrochloride (subcutaneous injection; 100 mg/kg; 3 times a day; 30 days) significantly decreases the number of lesions in mouse footpad with Nocardia brasiliensis .

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Animal Model: Female BALB/c mice with Nocardia brasiliensis in the right hind footpad
Dosage: 100 mg/kg
Administration: Subcutaneous injection; 3 times a day; 30 days
Result: Reduced the production of lesions in mice.
[target]

Topoisomerase II

36.7 μM ()

[storage]

Store at -20°C
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