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ChemicalBook--->CAS DataBase List--->1210538-56-9

1210538-56-9

1210538-56-9 Structure

1210538-56-9 Structure
IdentificationBack Directory
[Name]

RU-TRAAK-2
[CAS]

1210538-56-9
[Synonyms]

RU-TRAAK-2
[Molecular Formula]

C19H17N3OS
[MOL File]

1210538-56-9.mol
[Molecular Weight]

335.42
Chemical PropertiesBack Directory
[Boiling point ]

575.5±35.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO : 50 mg/mL (149.07 mM; Need ultrasonic)
[form ]

Solid
[pka]

11.95±0.46(Predicted)
[color ]

White to yellow
Spectrum DetailBack Directory
[Spectrum Detail]

RU-TRAAK-2(1210538-56-9)1HNMR
Hazard InformationBack Directory
[Biological Activity]

RU-TRAAK-2 is a completely reversible TRAAK (TWIK-related arachidonic acid-stimulated K+ channel) inhibitor. RU-TRAAK-2 exerts no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2)[1].
[References]

[1]. Su Z, et al. Novel cell-free high-throughput screening method for pharmacological tools targeting K+ channels. Proc Natl Acad Sci U S A. 2016;113(20):5748-5753.
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