Identification | Back Directory | [Name]
5-O-Desmethyl Donepezil | [CAS]
120013-57-2 | [Synonyms]
1-Benzyl-4-[(5-hydroxy-6-methoxy-1-oxo-indan-2-yl)methylpiperidine | [Molecular Formula]
C23H27NO3 | [MOL File]
120013-57-2.mol | [Molecular Weight]
365.47 |
Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
170-172°C | [Boiling point ]
545.3±50.0 °C(Predicted) | [density ]
1.190±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [pka]
8.16±0.40(Predicted) | [CAS DataBase Reference]
120013-57-2 |
Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
A metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase. | [Uses]
A metabolite of Donepezil, an inhibitor of acetylcholinesterase | [Definition]
ChEBI: 5-O-desmethyldonepezil is a member of the class of piperidines that is donepezil in which the 5-methoxy group has been demethylated to the corresponding hydroxy derivative. It is metabolite of donepezil, a drug used in the treatment of dementia. It has a role as a drug metabolite. It is a member of piperidines, a cyclic ketone, an aromatic ether and a member of guaiacols. |
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