| Identification | Back Directory | [Name]
2-AMINO-6-METHYLMERCAPTOPURINE | [CAS]
1198-47-6 | [Synonyms]
NSC 29420
6-Methylthioguanine
TIMTEC-BB SBB000228
S-Methyl-6-thioguanine
S6-Methyl-6-thioguanine
2-Amino-6-methylthiopurine
2-AMINO-6-METHYLMERCAPTOPURINE
6-Methylthio-7H-purine-2-amine
6-(methylthio)-1H-purin-2-amine
2-Amino-6-(methylthio)-9H-purine
6-(Methylthio)-9H-purine-2-amine
1H-Purin-2-amine, 6-(methylthio)-
2-Amino-6-methylmercaptopurine,95%
2-AMINO-6-METHYLMERCAPTOPURINE 95%
6-(Methylsulfanyl)-1H-purin-2-amine
6-(METHYLSULFANYL)-7H-PURIN-2-YLAMINE | [EINECS(EC#)]
214-833-4 | [Molecular Formula]
C6H7N5S | [MDL Number]
MFCD00044701 | [MOL File]
1198-47-6.mol | [Molecular Weight]
181.22 |
| Chemical Properties | Back Directory | [Appearance]
off-white crystalline powder | [Melting point ]
235.5°C | [density ]
1.403 (estimate) | [refractive index ]
1.4606 (estimate) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly, Sonicated) | [form ]
solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
off-white crystalline powder | [Uses]
A metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine. An effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer. | [Definition]
ChEBI: 6-methylthioguanine is a metabolite of thioguanine, a drug used in cancer chemotherapy. It has a role as a human xenobiotic metabolite. It is a member of 2-aminopurines and a thiopurine. It is functionally related to a tioguanine. | [Biochem/physiol Actions]
2-Amino-6-methylmercaptopurine is synthesized from 6-mercaptopurine by the S methylation activity of thiopurine methyl transferase (TMPT) enzyme. |
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