| Identification | Back Directory | [Name]
5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide | [CAS]
1189426-07-0 | [Synonyms]
[2H11]-Glipizide
5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide
Glipizide d11Q: What is
Glipizide d11 Q: What is the CAS Number of
Glipizide d11 Q: What is the storage condition of
Glipizide d11 Q: What are the applications of
Glipizide d11 | [Molecular Formula]
C21H16D11N5O4S | [MDL Number]
MFCD08705009 | [MOL File]
1189426-07-0.mol | [Molecular Weight]
456.603 |
| Hazard Information | Back Directory | [Description]
Glipizide-d11 is intended for use as an internal standard for the quantification of glipizide by GC- or LC-MS. Glipizide is a hypoglycemic agent. It inhibits ATP-sensitive potassium (KATP) channels in primary mouse pancreatic β cells (IC50 = 6.4 nM). Glipizide induces insulin release from isolated rat pancreatic tissue with an EC50 value of 40 nM. Dietary administration of glipizide (5 mg/kg per day for 10 days) increases the number of insulin receptors on isolated and purified mouse liver plasma membranes. It reduces plasma glucose and triglyceride, but not total cholesterol, levels and increases plasma insulin levels in a rat model of diabetes induced by a high-fat diet and streptozotocin (STZ; ) when administered orally at a dose of 5 mg/kg. Formulations containing glipizide have been used in the treatment of type 2 diabetes. | [Uses]
Labelled Glipizide (G410225). A sulfonylurea hypoglycemic agent. Used as an antidiabetic. | [storage]
Store at -20°C |
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