Identification | Back Directory | [Name]
BUSULFAN-D8 (TETRAMETHYLENE-D8) | [CAS]
116653-28-2 | [Synonyms]
GT-41-d8 Myleran-d Myleran-d8 CB-2041-d8 Misulban-d8 Busulfan-d8 Busulfex-d8 Busulphan-d8 Busulfan-D8(tetramethylene) BUSULFAN-D8 (TETRAMETHYLENE-D8) 1,4-Butanediol-d8-dimethanesulfonate Esters | [Molecular Formula]
C6H6D8O6S2 | [MDL Number]
MFCD06658695 | [MOL File]
116653-28-2.mol | [Molecular Weight]
254.35 |
Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
112-1140C | [storage temp. ]
-20°C Freezer | [solubility ]
DMF: 16.7 mg/ml,DMSO: 16.7 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Alkylating agent with antileukemic activity. Antineoplastic | [Description]
Busulfan-d8 is intended for use as an internal standard for the quantification of busulfan (Item No. 14843) by GC- or LC-MS. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent.1 It forms both intra- and interstrand crosslinks on DNA.2,3 In mammals, busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.4 |
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Company Name: |
TOSUN PHARM
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Tel: |
020-61855200 13326451905 |
Website: |
www.toref.cn/ |
Company Name: |
Energy Chemical
|
Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
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