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ChemicalBook--->CAS DataBase List--->1150310-15-8

1150310-15-8

1150310-15-8 Structure

1150310-15-8 Structure
IdentificationBack Directory
[Name]

(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile
[CAS]

1150310-15-8
[Synonyms]

Entacapone impurity H
-oxo-1-piperidinepropanenitrile
(2E)-3-(3,4-Dihydroxy-5-nitrophenyl
Entacapone Impurity 8(Entacapone EP Impurity A)
Entacapone Impurity 8(Entacapone EP Impurity H)
-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-&beta
Entacapone Impurity 24(Entacapone EP Impurity H)
(E)-3-(3,4-dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)prop-2-enenitrile
(αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile
1-Piperidinepropanenitrile, α-[(3,4-dihydroxy-5-nitrophenyl)methylene]-β-oxo-, (αE)-
(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile
[Molecular Formula]

C15H15N3O5
[MOL File]

1150310-15-8.mol
[Molecular Weight]

317.3
Chemical PropertiesBack Directory
[Melting point ]

207-208℃ (ethanol )
Hazard InformationBack Directory
[Uses]

(αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
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