| Identification | Back Directory | [Name]
Aprepitant-d4 | [CAS]
1133387-60-6 | [Synonyms]
Aprepitant-d4
[2H4]-Aprepitant
5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl-2,3,5,6-d4)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one | [Molecular Formula]
C23H17D4F7N4O3 | [MDL Number]
MFCD11977964 | [MOL File]
1133387-60-6.mol | [Molecular Weight]
538.451 |
| Chemical Properties | Back Directory | [Melting point ]
242-244°C | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly, Sonicated) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Aprepitant-d4 is a labeled analogue of Aprepitant (A729800), A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Aprepitant-d4 is a potential treatment for chemotherapy induced nausea and vomiting. | [storage]
Store at -20°C |
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| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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Pharma Affiliates
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172-5066494 |
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http://www.is0513.com/ShowSupplierProductsList694812/0.htm |
| Company Name: |
Simson Chemie
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09967773737 |
| Website: |
http://www.is0513.com/ShowSupplierProductsList461575/0.htm |
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