| Identification | Back Directory | [Name]
HIRUDIN (54-65) (DESULFATED) | [CAS]
113274-56-9 | [Synonyms]
Hirudin
GDFEEIPEEYLQ
HIRUDIN (54-65) (DESULFATED)
HIRUDIN FRAGMENT 54-65 NON-SULFATED
HIRUDIN (54-65) (DESULFATED) USP/EP/BP
GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN
H-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN-OH
L-Glutamine, glycyl-L-α-aspartyl-L-phenylalanyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-prolyl-L-α-glutamyl-L-α-glutamyl-L-tyrosyl-L-leucyl- | [Molecular Formula]
C66H93N13O25 | [MDL Number]
MFCD00076563 | [MOL File]
113274-56-9.mol | [Molecular Weight]
1468.52 |
| Chemical Properties | Back Directory | [Boiling point ]
1913.6±65.0 °C(Predicted) | [density ]
1.384±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [pka]
3.25±0.10(Predicted) | [Sequence]
H-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OH | [LogP]
-0.190 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Hirudin is the strongest thrombin retarder so far. It fuses with thrombin to produce a non-covalent nitric oxide synthase with a dissociation constant of the order of 10-12 and a very fast reaction rate. quick. Hirudin and thrombin have strong infectivity, 1μg can neutralize 5μg thrombin, and the molar ratio is 1:1. | [Uses]
Hirudin is a small protein (polypeptide) composed of 65-66 amino acids. Hirudin has a strong inhibitory effect on thrombin and is the strongest natural specific inhibitor of thrombin found so far.
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