| Identification | Back Directory | [Name]
2'- AND 3'-O-(4-BENZOYLBENZOYL)-ADENOSINE 5'-TRIPHOSPHATE TRIETHYLAMMONIUM SALT | [CAS]
112898-15-4 | [Synonyms]
benzoylbenzoyl-atp
Benzoylbenzoyl-ATP, Bz-ATP
BzATP triethylammonium salt
2'(3')-o-(4-benzoylbenzoyl)adeno
BENZOYLBENZOIC ADENOSINE 5'-TRIPHOSPHATE
2'-3'-O-(4-benzoylbenzoyl)adenosine*5'-triphospha
2'-3'-O-(4-BENZOYLBENZOYL)ADENOSINE5'-TR IPHOSPHATE
benzoylbenzoyl-ATP triethylammonium salt, mixed isomers
2'(3')-o-(4-benzoylbenzoyl)adenosine 5'-triphosphate triethylammonium salt
2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphatetri(triethylammonium)salt
2'- AND 3'-O-(4-BENZOYLBENZOYL)-ADENOSINE 5'-TRIPHOSPHATE TRIETHYLAMMONIUM SALT
Adenosine 5'-(tetrahydrogen triphosphate) 3'-(4-benzoylbenzoate) compd. with N,N-diethylethanamine | [Molecular Formula]
C30H39N6O15P3 | [MDL Number]
MFCD00058547 | [MOL File]
112898-15-4.mol | [Molecular Weight]
816.58 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
≤14 mg/ml in DMSO | [form ]
solid | [color ]
white to off-white | [Water Solubility ]
Soluble in water (supplied pre-dissolved at a concentration of 5mM) | [InChIKey]
HVOVBTNCGADRTH-WBLDMZOZSA-N |
| Hazard Information | Back Directory | [Uses]
2′(3′)-O-(4-Benzoylbenzoyl)adenosine 5′-triphosphate triethylammonium salt has been used as a P2X4 receptor agonist in rat kidney sections, type I diabetes induced rats and astrocyte?neuron coculture. It has also been used as a synthetic ATP analog in isotonic E3 medium. | [General Description]
2′(3′)-O-(4-Benzoylbenzoyl)adenosine 5′-triphosphate is a photoreactive analog of ATP. | [Biological Activity]
Prototypic P2X 7 receptor agonist that exhibits 5 - 10 fold greater potency than ATP (EC 50 = 0.7 μ M in HEK 293 cells). Exhibits partial agonist activity at P2X 1 (pEC 50 = 8.7) and P2Y 1 receptors and can be used as a photoaffinity label for ATPase. | [Biochem/physiol Actions]
2′(3′)-O-(4-Benzoylbenzoyl)adenosine 5′-triphosphate triethylammonium salt is a selective purinergic receptor (P2X) agonist. It is more potent than ATP at homodimeric P2X7 receptors. It also effectively activates P2X1, P2X2, and P2X3 receptors. Useful as a photoaffinity label for proteins and enzymes that bind ATP. | [storage]
Store at -20°C |
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