| Identification | Back Directory | [Name]
exo-IWR 1 | [CAS]
1127442-87-8 | [Synonyms]
exo-IWR 1
IWR-1-exo
rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-Methano-2H-isoindol-2-yl]-N-8-quinolinylbenzaMide
4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide
Benzamide, 4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-, rel- | [Molecular Formula]
C25H19N3O3 | [MDL Number]
MFCD18086912 | [MOL File]
1127442-87-8.mol | [Molecular Weight]
409.44 |
| Chemical Properties | Back Directory | [Boiling point ]
643.9±55.0 °C(Predicted) | [density ]
1.425±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Powder | [pka]
11.88±0.43(Predicted) | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Uses]
exo-IWR-1 is the enantiomer of IWR-1 (I941800). exo-IWR-1 is an SAR anticancer Wnt response inhibitor. Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditi
ons such as cancer, degenerative diseases, type II diabetes and osteopetrosis. | [Definition]
ChEBI: IWR-1-exo is a dicarboximide having an exo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. It is a weak axin stabilizer, an analogue of IWR-1-endo. It has a role as an axin stabilizer. It is a dicarboximide and a bridged compound. | [storage]
Store at RT |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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