Identification | Back Directory | [Name]
5-HYDROXYMETHYLCYTOSINE | [CAS]
1123-95-1 | [Synonyms]
5hmC 5-HYDROXYMETHYLCYTOS 5-Hydroxymethylcytosine 5-Hydroxymethylcytosinefreebase 6-amino-5-methylol-1H-pyrimidin-2-one 4-amino-5-methylol-3H-pyrimidin-2-one 5-(Hydroxymethyl)Cytosine Hydrochloride 4-AMINO-5-(HYDROXYMETHYL)PYRIMIDIN-2-OL 4-Amino-5-hydroxymethyl-2(1H)-pyrimidinone 5-HYDROXYMETHYLCYTOSINE ISO 9001:2015 REACH 4-AMINO-2-HYDROXY-5-HYDROXYMETHYLPYRIMIDINE 4-Amino-5-(hydroxymethyl)pyrimidin-2-ol ,97% 4-Amino-5-(hydroxymethyl)-2(1H)-pyrimidinone 6-amino-5-(hydroxymethyl)-1H-pyrimidin-2-one 4-aMino-5-(hydroxyMethyl)pyriMidin-2(1H)-one 4-amino-5-(hydroxymethyl)-3H-pyrimidin-2-one 6-azanyl-5-(hydroxymethyl)-1H-pyrimidin-2-one 2-Hydroxy-4-amino-5-(hydroxymethyl)pyrimidine 2(1H)-Pyrimidinone,6-amino-5-(hydroxymethyl)- 2(1H)-Pyrimidinone, 4-amino-5-(hydroxymethyl)- 2(1H)-Pyrimidinone, 4-amino-5-(hydroxymethyl)- (9CI) | [Molecular Formula]
C5H7N3O2 | [MDL Number]
MFCD00047369 | [MOL File]
1123-95-1.mol | [Molecular Weight]
141.13 |
Chemical Properties | Back Directory | [Melting point ]
>299.85°C | [Boiling point ]
258.15°C (rough estimate) | [density ]
1.3818 (rough estimate) | [refractive index ]
1.6190 (estimate) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [solubility ]
DMSO (Sparingly), Methanol (Slightly, Heated, Sonicated) | [form ]
Solid | [pka]
8.61±0.10(Predicted) | [color ]
Pale Yellow to Beige |
Hazard Information | Back Directory | [Chemical Properties]
Grey solid | [Uses]
5-(Hydroxymethyl)cytosine is a DNA pyrimidine nitrogen base.It may regulate gene expression or prompt DNA demethylation. 5-Hydroxymethylcytosine may be especially important in the central nervous system, as it is found in very high levels there. | [Definition]
ChEBI: A nucleobase analogue that is cytosine in which the hydrogen at position 5 is replaced by a hydroxymethyl group. |
|
|