| Identification | Back Directory | [Name]
DEOXYCHOLIC-2,2,4,4-D4 ACID | [CAS]
112076-61-6 | [Synonyms]
Deoxycholic acid-D
Deoxycholic-d4 Acid
2H4]-Deoxycholic acid
DEOXYCHOLIC-2,2,4,4-D4 ACID
Deoxycholic acid-2,2,4,4-d4
Deoxycholic Acid-[d4] (Solution)
Deoxycholic Acid-d4 MaxSpec? Standard
DEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL | [Molecular Formula]
C24H40O4 | [MDL Number]
MFCD00209707 | [MOL File]
112076-61-6.mol | [Molecular Weight]
392.58 |
| Chemical Properties | Back Directory | [Melting point ]
171-174 °C | [Fp ]
9℃ | [storage temp. ]
-20°C | [solubility ]
DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
Deoxycholic acid-d4 (DCA-d4) is intended for use as an internal standard for the quantification of DCA (Item Nos. 20756 | 18231) by GC- or LC-MS. DCA is a secondary bile acid that is formed via microbial transformation of cholic acid in the colon. It can be conjugated to glycine or taurine to produce glycodeoxycholic acid (GDCA; ) or taurodeoxycholic acid (TDCA; ), respectively, in hepatocytes. DCA (0.2% v/v) inhibits spore germination induced by taurocholic acid (TCA; ) in seven C. difficile strains, as well as inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells when used at a concentration of 0.02% v/v. It inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells when used at a concentration of 200 μM. Fecal and intestinal tissue levels of DCA are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet. Increased serum DCA levels have been found in patients with colorectal cancer. | [Uses]
Deoxycholic-2,2,4,4-d4 Acid (CAS# 112076-61-6) is a useful isotopically labeled research compound. | [Definition]
ChEBI: Deoxycholic acid-2,2,4,4-d4 is a deuterated compound and a deoxycholic acid. |
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