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LG 50643 is a muscarinic antagonist. | [in vivo]
Three successive pre- and postjunctional responses were observed. The potencies (-logEC50) of (+/-)-LG50643 for pre- and postjunctional muscarinic receptors were determined and compared with those of selective muscarinic antagonists. In addition, the affinity values of (+/-)-LG50643 for muscarinic-receptor subtypes were determined in radioligand binding experiments in cerebral cortex, heart and salivary glands of rat as target tissues for M1, M2 and M3 receptors, respectively._x000D_
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Reference: J Pharm Pharmacol. 1994 May;46(5):332-6. https://pubmed.ncbi.nlm.nih.gov/8083801/ | [target]
LG 50643 is a muscarinic antagonist. |
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CHEMICAL LAND21
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82- 2 -783 - 8063 |
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www.chemicalland21.com |
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