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ChemicalBook--->CAS DataBase List--->110764-79-9

110764-79-9

110764-79-9 Structure

110764-79-9 Structure
IdentificationBack Directory
[Name]

5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
[CAS]

110764-79-9
[Synonyms]

5'-O-DMT-2'-O-Me-rU-3'-CEDPA
2’-O-Methy-rUPhosphoramidite
2'-O-Methyl-rU phosphoramidite
5'-DMT-2'-OMe-rU Phosphoramidite
DMT-2′O-Methyl-rU Phosphoramidite
DMT-2'O-Me-rU Amidite 10g, Single
DMT-2'O-ME-RU AMIDITE 0.5G AB SINGLE
DMT-2'O-ME-RU AMIDITE 0.5G 89 SINGLE
2'-O-methyluridine-ce phosphoramidite*for abi
5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite
N-blocked-5'-O-DMT-2'-O-Me CED uridine phosphoramidite
2'-Deoxy-2'-O-Me-5'-O-DMT-Uridine-3'-CED PhosphoraMidite
5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methyl-Uridine-3'-CE-Phosphoramidite
5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidit
3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-METHOXYOXOLA
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine 3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite
Uridine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-Methyl-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite]
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
[EINECS(EC#)]

200-100-5
[Molecular Formula]

C40H49N4O9P
[MDL Number]

MFCD00792626
[MOL File]

110764-79-9.mol
[Molecular Weight]

760.82
Chemical PropertiesBack Directory
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

DMSO : 100 mg/mL (131.44 mM; Need ultrasonic)
[form ]

powder
[pka]

9.39±0.10(Predicted)
[color ]

white to off-white
[InChIKey]

UVUOJOLPNDCIHL-XKZJCBTISA-N
[SMILES]

C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,36,39,r|
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

DMT-2'O-Methyl-rU Phosphoramidite is a white to off-white powder and is used as a pharmaceutical intermediate for pharmaceutical synthesis and scientific research.
[Application]

2′O-Methyl RNA nucleoside including DMT-2′O-Methyl-rU Phosphoramidite can be advantageously incorporated in nucleic acid probes with RNA or DNA for in-vivo or in-vitro applications to convey nuclease resistance.The unique combination of properties of 2′O-Methyl RNA had found widespread use in the fields of:
Diagnostic probes
Aptamer and ribozyme development
Mixed 2′O-Methyl-RNA/DNA antisense molecules
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