| Identification | Back Directory | [Name]
1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE | [CAS]
110283-66-4 | [Synonyms]
ci966
CI966HCl
CI 966 hydrochlorid
CI 966 HYDROCHLORIDE
CI-966 hydrochloride
(CI966)
3-pyridinecarboxylicacid,1,2,5,6-tetrahydro-1-(2-(bis(4-(trifluoromethyl)phen
1-[2-[BIS(4-(TRIFLUOROMETHYL)PHENYL)METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID
1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid hydrochloride
1-[2-bis[4-(Trifluormethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydropyridine3-carboxylic acid hydrochloride
1-(2-(Bis(4-(trifluoromethyl)phenyl)methoxy)ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylicacidhydrochloride
1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE | [Molecular Formula]
C23H22ClF6NO3 | [MDL Number]
MFCD00889186 | [MOL File]
110283-66-4.mol | [Molecular Weight]
509.87 |
| Chemical Properties | Back Directory | [Melting point ]
240-244 °C | [storage temp. ]
Desiccate at RT | [solubility ]
Soluble to 10 mM in ethanol and to 100 mM in DMSO | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CI-966 Hydrochloride is highly selective for the cloned GABA transporter GAT-1. CI 966 Hydrochloride is a GABA transport inhibitor. | [Biological Activity]
Selective inhibitor of the GABA transporter GAT-1 (IC 50 values are 0.26 and 1.2 μ M at cloned human and rat GAT-1 respectively). Displays over 200-fold selectivity over GAT-2 and GAT-3. Centrally active upon systemic administration in vivo . Anticonvulsive and neuroprotective. | [storage]
Desiccate at RT |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
|