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ChemicalBook--->CAS DataBase List--->109053-09-0

109053-09-0

109053-09-0 Structure

109053-09-0 Structure
IdentificationBack Directory
[Name]

Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln
[CAS]

109053-09-0
[Synonyms]

Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln
L-Glutamine, glycyl-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-
[Molecular Formula]

C31H53N9O10
[MDL Number]

MFCD30602097
[MOL File]

109053-09-0.mol
[Molecular Weight]

711.81
Chemical PropertiesBack Directory
[Boiling point ]

1220.2±65.0 °C(Predicted)
[density ]

1.267±0.06 g/cm3(Predicted)
[pka]

3.25±0.10(Predicted)
Hazard InformationBack Directory
[Biological Activity]

Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln（GPLGIAGQ）, an MMP2 cleavable polypeptide, has been used as a stimulus-sensitive linker in both liposomes and micellar nanocarriers for MMP2-triggered tumor targeting studies. GPLGIAGQ can be used to synthesize unique MMP2-targeted photosensitizers in photodynamic therapy (PDT).
[in vitro]

GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization.

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